Searchable abstracts of presentations at key conferences on calcified tissues

ba0001pp161 | Cancer and bone: basic, translational and clinical | ECTS2013

Effect of zoledronic acid on bone mineral density in premenopausal women receiving neoadjuvant or adjuvant therapies for breast cancer: the ProBONE II Study

Hadji Peyman , Kauka Anette , Bauer Thomas , Birkholz Katrin , Baier Monika , Muth Mathias Muth , Ziller May

Introduction: Bone mineral density (BMD) evaluations have shown that adjuvant chemotherapy or endocrine therapy (ET) for early breast cancer (BC) is associated with accelerated BMD loss and increased fracture risk. In recent studies, zoledronic acid (ZOL) increased BMD in premenopausal and postmenopausal women with BC, and improved disease-free survival in some patient subsets compared with no ZOL. The purpose of the current study was to investigate the effect of adjuvant trea...